منابع مشابه
Histamine release following pancuronium. A case report.
A case report is presented in which an asthmatic patient appears to have developed bronchospasm after being given pancuronium. A review of the literature indicates that this agent is the least likely of muscle relaxants in clinical use to provoke such a response, and that no such case has hitherto been reported. It is suggested that caution should be exercised even when pancuronium is used in a...
متن کاملExtended neuromuscular blockade with mivacurium following pancuronium.
A 21-year-old female weighing 55 kg was anaesthetized for facial reconstruction. After an initial bolus of pancuronium 5 mg and top-up doses of 2 mg at 135 min and 1 mg at 290 min and 335 min, no further relaxant was given for 130 min at which time neuromuscular transmission appeared fully recovered with a full train-of-four twitches and a sustained response to 50 Hz stimulation of the posterio...
متن کاملAnaphylatoxin-induced histamine release with human leukocytes: studies of C3a leukocyte binding and histamine release.
Purified human C3a and synthetic COOH-terminal peptides of C3a, i.e., a pentapeptide, Leu-Gly-Leu-Ala-Arg (5R), and an octapeptide, Ala-Ala-Ala-Leu-Gly-Leu-Ala-Arg (8R) induced histamine release from human basophil granulocytes. On a molar basis, 5R was one-tenth and 8R was one-fifth as active as C3a in causing histamine release. It was found that 125I-C3a binds to whole leukocytes, interacting...
متن کاملConditions for tracheal intubation following fazadinium and pancuronium.
Intubating conditions were studied in two groups of patients who received either fazadinium 1 mg/kg or pancuronium 0.1 mg/kg (group 1), or either fazadinium 0.5 mg/kg or pancuronium 0.08 mg/kg (group 2). In group 1 intubating conditions were studied at 30, 45, 60 and 75 s after injection of the relaxant drug, and in group 2 at 60 s after injection. Fazadinium provided better intubating conditio...
متن کاملThe release of histamine by sinomenine.
Sinomenine is an alkaloid contained in the root of Sinomenium acutum Rehd. et Wilson (Fam. Menishermaceae), growing wild in southern Japan, and has long been used as a home remedy for neuralgia and rheumatism. It has a chemical structure similar to that of morphine, as shown left (1). Ishiwari (2, 3), who first isolated this alkaloid and studied its pharmacological actions, found that sinomenin...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1973
ISSN: 0007-0912
DOI: 10.1093/bja/45.5.518